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STEREOSELECTIVE ANALYSIS & CHROMATOGRAPHY
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Principles of stereochemistry
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PRINCIPLES of CHIRAL SEPARATION
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Indirect LC enantiomer separation
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Direct LC enantiomer separation
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General elution modes
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CHIRAL STATIONARY PHASES:
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1. Coated Polysaccharide-based CSPs
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2. Immobilized polysaccharide CSPs
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> Solvent compatibilities of 1 and 2
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3. Protein CSPs
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4. Synthetic polymer CSPs
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5. Cyclodextrin(CD)-based CSPs
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6. Macrocyclic antibiotics CSPs
- 7. Donor-acceptor (Brush/Pirkle-type) CSPs
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8. Chiral crown-ether CSPs
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9. Chiral anion-exchangers
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10.Chiral ligand-exchange CSPs
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Column selection & method devel.
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Analysis of enantiomer composition
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Enantiomeric impurity determination
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Links to important column suppliers
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