3. Protein CSPs
Abstract
Protein phases have been an important class of CSPs in the early pioneering days of enantiomer separation.
Level
Basic
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STEREOSELECTIVE ANALYSIS & CHROMATOGRAPHY
Principles of stereochemistry
PRINCIPLES of CHIRAL SEPARATION
Indirect LC enantiomer separation
Direct LC enantiomer separation
General elution modes
CHIRAL STATIONARY PHASES:
1. Coated Polysaccharide-based CSPs
2. Immobilized polysaccharide CSPs
> Solvent compatibilities of 1 and 2
3. Protein CSPs
4. Synthetic polymer CSPs
5. Cyclodextrin(CD)-based CSPs
6. Macrocyclic antibiotics CSPs
7. Donor-acceptor (Brush/Pirkle-type) CSPs
8. Chiral crown-ether CSPs
9. Chiral anion-exchangers
10.Chiral ligand-exchange CSPs
Column selection & method devel.
Analysis of enantiomer composition
Enantiomeric impurity determination
Links to important column suppliers
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